DNA Repair Content

Experiments in Yeast Hint at Possible Origins of Cancer and Autism

Andy Fell — October 24, 2023 - 4:51pm

Cancer often starts with the reshuffling of DNA—akin to scrambling the pages of a dictionary. Exactly how this happens has long been a mystery. But researchers in the ��Ƶ College of Biological Sciences have now arrived at one promising explanation.

Understanding Why BRCA2 Is Linked to Cancer Risk

Andy Fell — April 03, 2023 - 10:00am

A new study shows exactly how the gene BRCA2, linked to susceptibility to breast and ovarian cancer, functions to repair damaged DNA. By studying BRCA2 at the level of single molecules, researchers at the ��Ƶ, Davis, have generated new insights into the mechanisms of DNA repair and the origins of cancer. The work was published the week of March 27 in the Proceedings of the National Academy of Sciences.

Single-protein Images Show How E. coli Repairs DNA While Replicating It

Andy Fell — September 22, 2022 - 11:34am

The success of E. coli bacteria depends on their ability to multiply very rapidly by dividing into new cells. The bacteria can divide as quickly as they can make an entire new copy of their DNA while minimizing errors. New work from researchers at the ��Ƶ, Davis College of Biological Sciences answers a key question about how E. coli fixes damage to DNA in the middle of duplicating it.